Holly Springs, NC, US

Fujifilm building exterior

Holly Springs,  a global biomanufacturing hub located in Wake County, North Carolina, is home of FUJIFILM Diosynth Biotechnologies’ largest end-to-end cell culture biopharmaceutical CDMO facility in North America.

Scheduled to be operational in 2025, this facility will offer large-scale cell culture manufacturing of bulk drug substance production with 8 X 20,000 L bioreactors. And before this project is even completed, Fujifilm announced a $1.2bn expansion for drug substance manufacturing.


Every once in a while, a chance comes by to build a workplace culture that is unique, energetic, and united by a common purpose.  This is happening at our site in Holly Springs, NC.  Laser focused on delivering best-in-class design, processes, and organizational structure, we are building a community of colleagues who realize they are working on something that has never been done before.

They are passionate about impacting patients, passionate about pushing the envelope of innovation and passionate about maintaining a highly engaging and enthusiastic teamwork environment. 


Holly Springs, North Carolina, is an up-and-coming area where you can experience community in every sense of the word.  Conveniently located near the state’s capital city of Raleigh, you can easily enjoy the metropolitan scene of a big city, or you can bathe in the warmth of true Southern hospitality with the small-town feel.  The area is quickly becoming known as a mecca for those seeking high-tech occupations, and we are in the center of it all.


As a keystone for our global climate strategy, Partners for the Planet, we are taking the opportunity to incorporate leading-edge sustainability aspects by design with this Greenfield project. We set strong targets early on, and we are steadily building our way to achieving them.

Why Holly Springs

Sustainability At a Glance

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Renewable Energy for Electricity & Gas

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Reduction in Potable Water Use

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Diversion of Construction Debris from Landfill

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Diversion of Operational Waste from Landfill

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Reduction Through Reuse / Reclaim

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Tons of Construction Waste Diverted


What does Partners for Life look like in action? For us it means fostering an integrated, supportive local ecosystem grounded in trust. We focus on workforce development, transportation improvements, sustainability, and community involvement, building that quality of place that makes Holly Springs unique and a community role-model.

Active engagement with strong community partners brings greater success for all, and our local partners include:


  • Economic Development Partnership of NC
  • Holly Springs Chamber of Commerce
  • Japan-America Society of NC
  • NC Business Committee on Education
  • NC Biotechnology Center
  • NC Community Colleges
  • NC Department of Commerce
  • Raleigh Chamber of Commerce
  • Wake Early College
  • Regional Transportation Alliance
  • Triangle Women in STEM
  • Wake Tech
  • Wake County Chamber of Commerce


  • ISPE Carolina – South Atlantic Chapter
  • Town of Holly Springs
  • NC Central University
  • NC State University
  • The NC Biosciences Organization
  • Wake County Economic Development
  • Wake County Public School System
  • RDU – International Airport
  • Research Triangle Regional Partnership
  • Business Sustainability Roundtable