BPI part of Biotech Week Boston

FUJIFILM Diosynth Biotechnologies is excited to be attending BPI part of Biotech Week Boston, Live in person September 20-23 at the Boston Convention and Exhibition Center, Boston, Ma. Connect with the Commercial Development team in person or virtually to learn more about our capabilities and how we could help you advance and deliver tomorrow’s medicines.

Join our presentation Wednesday – September 22, 2021, 11:30 am EDT
Sharyn Farnsworth, Principal Scientist and Group Leader Upstream Process Development-Cell Culture team , FUJIFILM Diosynth Biotechnologies, North Carolina

Commercial Scale Insect Cell Culture: Opportunity and Challenges in a CHO centric world

• A strategy for scale up and manufacture of a recombinant protein from Insect Cell Culture (ICC) using a Baculovirus Expression Vector System (BEVS) should be mapped out during the earliest stages of process development. The challenges of recombinant protein expression using ICC/BEVS production systems are different to more commonly used expression systems such as CHO and few vendors have the necessary scale-up experience to perform these assessments. The challenges include overcoming the inherent inconsistency of production media used for ICC, defining the appropriate cell cycling strategy and, most importantly, the defining viral infection strategy. Keeping a line of sight to manufacturing helps to define the manufacturing process and ensure it is reliable and robust.

For the full agenda and registration click here